fig1

Figure 1. An overview of the basal ganglia neuroanatomy and primary motor circuits. Ablative surgery options include pallidotomy - destroying the global pallidus (GPE, GPI in maroon and pink, respectively), thalamotomy - destroying the thalamus (purple), and subthalamotomy - destroying the subthalamic nucleus (STN, blue). Procedures can either be bilateral or unilateral and are done to reduce excessive inhibitory output from the internal globus pallidus (pink) and substantia nigra reticulata (green), and their respective pathways shown in red. Image provided by Harris et al.^[72] 2020