fig1

Figure 1. Physiological sex differences in male and female microglia. A: male microglia have an enlarged soma and more reactiveness in physiological conditions than female microglia. These cells have more pro-inflammatory responses, higher migration capacity, and enhanced MHCI, MHCII, and P2Y12 constitutive expression; B: female microglia, on the other hand, have a higher phagocytic capacity and higher gene expression of cell repair and inflammatory control genes