fig4

A potential role of karyopherin a2 in the impaired maturation of dendritic cells observed in glioblastoma patients

Figure 4. Correlations bar diagram. The y axis shows the relative proportion of our cohort with different karyopherin a2 (KPNA2) expression demonstrating (a)*high (≥ 5.9 (median) vs. **low (< 5.9 cells/μL) DCs and (b) ***mutant vs. ****wild type isocitrate dehydrogenase-1 (IDH-1) R132H status. (a) All patients with low KPNA2 (< 5%) compared to only 33.3% of the patients with KPNA2 ≥ 5% demonstrated DCs high (P = 0.077). (b) Mutant IDH-1 status was seen more frequently in patients with low (< 5%) than in those with KPNA2 ≥ 5% (66.7% vs. only 7.7%, P = 0.071)

Neuroimmunology and Neuroinflammation
ISSN 2349-6142 (Online) 2347-8659 (Print)

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