fig3

A novel method for evaluating microglial activation using ionized calcium-binding adaptor protein-1 staining: cell body to cell size ratio

Figure 3. Potential markers for microglial activation in young and old rats with or without surgery. (a) The corrected optical density as marker for microglia activation; (b) The percentage of activated microglia (with an activation stage ≥ 3) based on visual characterization. (c) The cell body to cell size ratio (%) as marker for microglia activation. YC: young control; YS: young surgery; OC: old control; OS: old surgery. **P < 0.01 and ***P < 0.001 compared to young rats. +P < 0.05 and ++P < 0.01 compared to age matched controls

Neuroimmunology and Neuroinflammation
ISSN 2349-6142 (Online) 2347-8659 (Print)

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