Topic: Emerging Frontiers in Tumor Angiogenesis: Mechanisms, Therapeutic Strategies, and Future Challenges
Guest Editor(s)
Prof. Theresa L. Whiteside
Departments of Pathology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Special Issue Introduction
Dear Colleagues,
Tumor angiogenesis, the process of developing new blood vessels to support tumor growth, has long been recognized as a critical hallmark of cancer. The understanding of the complex mechanisms underlying tumor angiogenesis has led to significant advancements in cancer treatment strategies. However, emerging frontiers in this field continue to unveil novel insights, presenting both new challenges and opportunities for future research and therapy. This Special Issue will focus on the complex mechanisms of tumor angiogenesis, which are orchestrated by a variety of molecular players, including the key regulator known as vascular endothelial growth factor (VEGF). The signals from the tumor microenvironment add further complexity to this process, as not only endothelial cells and tumor cells but also immune cells and stromal cells actively participate in angiogenic processes by secreting pro-angiogenic factors and remodeling the extracellular matrix.
Studying the process of tumor angiogenesis has uncovered fundamental mechanisms driving tumor growth and provided a foundation for the development of anti-angiogenic therapies. The continuous exploration of emerging frontiers in this field holds great promise for improved cancer treatment. Overcoming challenges such as treatment resistance and treatment-related toxicities will be essential to optimize therapeutic strategies. The integration of novel technologies and personalized medicine approaches, in particular, will shape the future of tumor angiogenesis research and hopefully accelerate the development of more effective and targeted cancer therapies.
We sincerely hope that your contribution to this Special Issue will be a positive experience for both you and the angiogenesis research community. We warmly invite you to contribute your research to this Special Issue on “Emerging Frontiers in Tumor Angiogenesis: Mechanisms, Therapeutic Strategies, and Future Challenges”.
Tumor angiogenesis, the process of developing new blood vessels to support tumor growth, has long been recognized as a critical hallmark of cancer. The understanding of the complex mechanisms underlying tumor angiogenesis has led to significant advancements in cancer treatment strategies. However, emerging frontiers in this field continue to unveil novel insights, presenting both new challenges and opportunities for future research and therapy. This Special Issue will focus on the complex mechanisms of tumor angiogenesis, which are orchestrated by a variety of molecular players, including the key regulator known as vascular endothelial growth factor (VEGF). The signals from the tumor microenvironment add further complexity to this process, as not only endothelial cells and tumor cells but also immune cells and stromal cells actively participate in angiogenic processes by secreting pro-angiogenic factors and remodeling the extracellular matrix.
Studying the process of tumor angiogenesis has uncovered fundamental mechanisms driving tumor growth and provided a foundation for the development of anti-angiogenic therapies. The continuous exploration of emerging frontiers in this field holds great promise for improved cancer treatment. Overcoming challenges such as treatment resistance and treatment-related toxicities will be essential to optimize therapeutic strategies. The integration of novel technologies and personalized medicine approaches, in particular, will shape the future of tumor angiogenesis research and hopefully accelerate the development of more effective and targeted cancer therapies.
We sincerely hope that your contribution to this Special Issue will be a positive experience for both you and the angiogenesis research community. We warmly invite you to contribute your research to this Special Issue on “Emerging Frontiers in Tumor Angiogenesis: Mechanisms, Therapeutic Strategies, and Future Challenges”.
Submission Deadline
20 Dec 2023
Submission Information
Ten articles in the Special Issue are exempt from article processing charges.
For Author Instructions, please refer to https://www.oaepublish.com/vp/author_instructions
For Online Submission, please login at https://oaemesas.com/login?JournalId=vp&SpecialIssueId=vp230616
Submission Deadline: 20 Dec 2023
Contacts: Alisa Wang, Assistant Editor, alisa@vpjournal.net
