Topic: Microbial Pathogenesis in Inflammatory Bowel Diseases

This special issue will delve into the intricate interplay between microbial agents and the development of inflammatory bowel diseases (IBD). In recent years, there has been a growing recognition of the pivotal role that various microbes play in the etiology and progression of IBD. This special issue aims to bring together cutting-edge research and insights into the mechanisms through which microbial factors contribute to the pathogenesis of these complex gastrointestinal disorders.

 

The special issue covers several key subtopics:

1. Gut Microbiota Dysbiosis and IBD: Investigate changes in gut microbiota composition in IBD patients, examining how these changes trigger inflammation;

2. Microbial Modulation of Immune Responses: Explore interactions between gut microbes and the immune system, focusing on how microorganisms influence IBD-related immune responses;

3. Pathogenic Microbes: Study specific microorganisms like adherent-invasive Escherichia coli (AIEC) and their roles in disrupting gut homeostasis and causing IBD;

4. Mucosal Barrier Integrity and Microbes: Examine how gut microbes affect the intestinal barrier's integrity and its link to inflammation;

5. Microbial Metabolites and IBD: Investigate microbial metabolites like short-chain fatty acids and their impact on IBD and potential therapeutic uses;
6. Diet and host-microbial interactions and their regulation of inflammation in IBD.

Inflammatory bowel diseases (IBD), gastrointestinal disorders, gut microbiota dysbiosis, immune responses, pathogenic microbes, mucosal barrier integrity, microbial metabolites

31 Aug 2024