Special Issue

Topic: Pharmacogenomic Approaches to Targeted Cancer Therapies
A Special Issue of Journal of Translational Genetics and Genomics
ISSN 2578-5281 (Online)
Submission deadline: 30 Apr 2024
Guest Editor
Special Issue Introduction
Cancer is a genomic disease, where hereditary and acquired mutations play pivotal roles in its development. Over the past decade, targeted therapies, designed to address cancer-causing mutated genes and abnormal proteins, have revolutionized the treatment of both solid and hematologic malignancies. These targeted therapies include: (1) small molecules tailored to selectively target particular mutations or defects; (2) immunotherapies that achieve improved responses in biomarker-selected populations; (3) monoclonal antibodies and drug-antibody conjugates directed at overexpressed proteins; and (4) cell-based therapies. To assess cancers comprehensively, next-generation sequencing is now routine practice, and treatments are personalized based on the genomic make-up of the cancer. In addition, the field of pharmacogenetics, which examines genetic polymorphisms in drug-metabolizing enzymes or drug targets, offers insights into tailoring cancer treatments by influencing both treatment response and associated toxicity and represents an additional avenue for personalizing cancer treatments.
This Special Issue will highlight innovative studies and review articles that explore new developments in targeted therapies and the better use of existing therapies through pharmacogenetics.
This Special Issue will highlight innovative studies and review articles that explore new developments in targeted therapies and the better use of existing therapies through pharmacogenetics.
Keywords
Cancer, pharmacogenomics, precision medicine
Submission Deadline
30 Apr 2024
Submission Information
For Author Instructions, please refer to https://www.oaepublish.com/jtgg/author_instructions
For Online Submission, please login at https://www.oaecenter.com/login?JournalId=jtgg&IssueId=jtgg2404301723
Submission Deadline: 30 Apr 2024
Contacts: Jixiang Zhao, Assistant Editor, jixiang.zhao@jtggjournal.com
Published Articles
Coming soon