Special Issue

Topic: Animal Models of Different Species for Investigating Neurodegenerative Diseases

A Special Issue of Ageing and Neurodegenerative Diseases

ISSN 2769-5301 (Online)

Submission deadline: 31 May 2022

Guest Editor(s)

Prof. Xiao-Jiang Li
GHM Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong, China.

Special Issue Introduction

Animal models are essential to the investigation of neurodegenerative diseases and the development of effective treatment. Genetically modified rodents have been widely used to model neurodegenerative diseases and provided important insights into disease pathogenesis. Recently developed gene-editing tool CRISPR-Cas9 also allowed the generation of large animal (rabbit, pig, monkey) models that can recapitulate important pathological features seen in the patient brains. This Special Issue will discuss the strengths and limitations of animal models of different species and provide an overview for using animal models to better understand the pathogenesis of neurodegenerative diseases and to develop effective therapies.

Submission Deadline

31 May 2022

Submission Information

For Author Instructions, please refer to https://oaepublish.com/and/author_instructions

For Online Submission, please login at https://oaemesas.com/login?JournalId=and&IssueId=and211119

Submission Deadline: 31 May 2022

Contacts: Monica Wang, Managing Editor, editorialoffice@ageneudisjournal.com

Published Articles

Open Access Editorial

Animal models for research on neurodegenerative diseases

Ageing Neur Dis 2023;3:17.
DOI: 10.20517/and.2023.24
Available online: 27 Aug 2023
Open Access Review

Rat models of major neurodegenerative disorders

Ageing Neur Dis 2022;2:17.
DOI: 10.20517/and.2022.19
Available online: 18 Oct 2022
Open Access Perspective

Genome-edited rabbit, a prospective alternative model for neurological diseases

Ageing Neur Dis 2022;2:16.
DOI: 10.20517/and.2022.15
Available online: 20 Sep 2022
Open Access Review

Genetically engineered pig models of neurological diseases

Ageing Neur Dis 2022;2:13.
DOI: 10.20517/and.2022.13
Available online: 31 Jul 2022
Open Access Review

Modeling neurodegenerative diseases using non-human primates: advances and challenges

Ageing Neur Dis 2022;2:12.
DOI: 10.20517/and.2022.14
Available online: 24 Jul 2022
Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)


All published articles will be preserved here permanently:



All published articles will be preserved here permanently: