- Dr. E. Melinda Mahabee-Gittens
- Division of Emergency Medicine, Cincinnati Children’s Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
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- Dr. Ata Rafiee
- Department of Medicine, University of Alberta, Edmonton, Canada.
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- Dr. Mohammad Hoseini
- Research Center for Health Sciences, Institute of Health, Department of Environmental Health, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
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Special Issue Introduction
Nowadays, humans are potentially exposed to various pollutants and chemicals through environmental and occupational exposures. These exposures could occur through three main routes: inhalation, ingestion, and dermal contact. Exposure assessment of pollutants in environmental and occupational settings can be done by characterizing environmental concentrations in different environments and/or working scenarios (i.e., different working tasks) and subsequently assessing environmental and/or occupational exposures by considering the lifestyle and working patterns of individuals such as time spent in microenvironments or working scenario. The body burden resulting from environmental and occupational exposures is determined by various factors, such as the pollutant’s concentration and timing of exposure, as well as individual factors, such as uptake, metabolism, and excretion rates.
Human biomonitoring is, by definition, the monitoring of exposures to pollutants and their effects on the body by measuring the concentrations of pollutants or their metabolites in human matrices such as blood, urine, hair, saliva, nails, etc. Human biomonitoring data directly reﬂect the total body burden or biological effect resulting from all routes of exposure and interindividual variability in exposure levels, metabolism, and excretion rates. It has been widely used as a reliable complementary approach in the exposure characterization of pollutants in environmental and occupational contexts. In addition, human biomonitoring can help assess the possible adverse health effects attributable to environmental and occupational exposures by employing makers of health effects such as oxidative stress and DNA damage, which are important in developing adverse health endpoints such as cardiovascular disease, pulmonary impairments, and cancer initiation and development.
The present special issue entitled “Human Biomonitoring and Biomarkers Exploration in Environmental and Occupational Exposure Assessment” will focus on environmental and occupational exposure assessment of pollutants using the human biomonitoring approach. Potential topics include, but are not limited to:
- Assessment of environmental and occupational exposures using biomarkers or environmental markers of exposure.
- Exploration of biomarkers, environmental markers, or diagnostic tests to assess the health effects attributable to environmental or occupational exposures.
- Investigating the associations of internal exposures to environmental exposures and the relevant exposure pathways.
- Analytical and methodological advances in human biomonitoring.
- Assessment of the epidemiology and/or biomarker or environmental marker patterns of environmental or occupational exposures.
We cordially invite all researchers in the field of human biomonitoring to submit your submissions (i.e., original research papers, review articles, highlights, commentaries, and editorials) for publication in this Special Issue.
Human biomonitoring, biomarkers, exposure assessment, health risk assessment
Submission Deadline31 Mar 2023