fig7

Figure 7. SDT and CDT. (A) The Pt/N-CD@TiO_2-x p-n junction platform integrates platinum-crosslinked nitrogen-doped carbon quantum dots (Pt/N-CDs) and OVs-rich TiO_2-x nanosheets, enabling glutathione (GSH) detection/depletion and enhanced sonodynamic therapy (SDT); (B) Tumor growth curves of the mice after different treatments (n = 5); (C) Survival curves of mice after various treatments. (Reproduced with permission^[54]. Copyright 2021, Wiley); (D) Synthesis of OVs-rich BiO_2-x nanosheets for CDT; (E) Free radical regulation of OVs-rich BiO_2-x nanosheets in cancer and noncancerous cells associated with the formation of immunosuppressive TME; (F) 4T1 tumor growth curves with different treatments (n = 5); (G) Body weight changes following treatments. (Reproduced with permission^[116]. Copyright 2021, Wiley); (H) Cu_2-xO@TiO_2-y z-scheme junctions for enhanced CDT-SDT combination tumor therapy; (I) Tumor growth curves of mice after different treatments; (J) Survival growth curves of mice after different treatments. (Reproduced with permission^[49]. Copyright 2022, Elsevier). ^**P < 0.01, ^***P < 0.001. OVs: Oxygen vacancies; CDT: chemodynamic therapy; ROS: reactive oxygen species; US: ultrasound; NSs: nanosheets; TME: tumor microenvironment; GSSG: glutathione disulfide.