scheme3
From: Acyl transfer-enabled catalytic asymmetric Michael addition of α-hydroxy-1-indanones to nitroolefins
Scheme 3. Reaction scope. Reaction conditions: Unless otherwise noted, all reactions were conducted with 5 mol% of L4, 10 mol % of ZnEt2, 0.20 mmol 1 and 0.20 mmol 2 in 2 mL MeCN. Isolated yields. The diastereomeric ratio parameter of 3 was detected by 1H NMR of the crude reaction mixture. The enantiomeric excess (ee) value was determined by HPLC analysis.
