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From:  Unraveling the tau puzzle: a review of mechanistic targets and therapeutic interventions to prevent tau pathology in Alzheimer's disease
Unraveling the tau puzzle: a review of mechanistic targets and therapeutic interventions to prevent tau pathology in Alzheimer's disease

Figure 6. Therapeutic modulators of tau propagation through intercellular organelle systems. (A) Myosin-10 blockers inhibit nanotube formation to inhibit intercellular propagation of pathologic tau[48-51]; (B) nSMase2 silencing and delivery of GW4869 inhibit exosome formation to prevent the exosomal release of tau[52]. Created with BioRender.com.

Ageing and Neurodegenerative Diseases
ISSN 2769-5301 (Online)
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