fig1

Figure 1. Inflammatory analytes. (A) CCL2 was elevated in sera of patients with ALS compared with sera from age-matched HC); (B) CCL2 was elevated in rapidly progressing patients compared with slowly progressing patients; CCL2 was elevated in slowly progressing patients compared with HC; (C) IL-18 was elevated in patients compared with HC; (D) IL-18 was elevated in rapidly progressing patients compared with slowly progressing patients; IL-18 was elevated in slowly progressing patients compared with HC; (E - G) CCL2 and IL-18 correlated with disease progression but did not correlate with each other. *P < 0.05, ** P < 0.01, *** P < 0.001, and n.s.: not significant.