fig3

Figure 3. (A) Mitochondrial Fission-Fusion Patterns in AD; (B) Mitochondrial Ca2+ Homeostasis Patterns in AD. DRP1: Dynamin-related protein-1; FIS1: fission protein 1; MCU: mitochondrial calcium uniporter; MFN1: mitofusin1; MFN2: mitofusin2; mPTP: mitochondrial permeability transition pore; NCLX: mitochondrial Na+/Ca2+/Li+ exchanger; OPA1: mitofusin1; ROS: reactive oxygen species; VDAC: voltage-dependent anion selective channel; ΔΨm: mitochondrial membrane potential.