REFERENCES

1. Basso C, Aguilera B, Banner J, et al. Guidelines for autopsy investigation of sudden cardiac death: 2017 update from the Association for European Cardiovascular Pathology. Virchows Arch. 2017;471:691-705.

2. Rubart M. Mechanisms of sudden cardiac death. J Clin Investig. 2005;115:2305-15.

3. Hayashi M, Shimizu W, Albert CM. The spectrum of epidemiology underlying sudden cardiac death. Circ Res. 2015;116:1887-906.

4. Tfelt-Hansen J, Garcia R, Albert C, et al. Risk stratification of sudden cardiac death: a review. Europace. 2023;25:euad203.

5. Ma H, Xu F, Liu L, et al. Age and sex differences in the risk of sudden cardiac death in patients with hypertrophic cardiomyopathy: a multi-centre cohort study. Vasc Health Risk Manag. 2025;21:251-67.

6. Butters A, Arnott C, Sweeting J, Winkel BG, Semsarian C, Ingles J. Sex disparities in sudden cardiac death. Circ Arrhythm Electrophysiol. 2021;14:e009834.

7. Skjelbred T, Rajan D, Svane J, Lynge TH, Tfelt-Hansen J. Sex differences in sudden cardiac death in a nationwide study of 54 028 deaths. Heart. 2022;108:1012-8.

8. Arandjelovic A, Pavlovic S, Mazic S, Aleksandric B. Sudden cardiac death in athletes. Srp Arh Celok Lek. 2004;132:194-7.

9. Sessa F, Chisari M, Salerno M, et al. Congenital heart diseases (CHDs) and forensic investigations: searching for the cause of death. Exp Mol Pathol. 2024;137:104907.

10. Sacco MA, Mastrangelo H, Neri G, Aquila I. Post-mortem biomarkers in sudden cardiac death: from classical biochemistry to molecular autopsy and multi-omics forensic approaches. Int J Mol Sci. 2026;27:670.

11. Sessa F, Esposito M, Messina G, Di Mizio G, Di Nunno N, Salerno M. Sudden death in adults: a practical flow chart for pathologist guidance. Healthcare. 2021;9:870.

12. Zeppenfeld K, Tfelt-Hansen J, De Riva M, et al. 2022 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J. 2022;43:3997-4126.

13. Kelly KL, Lin PT, Basso C, et al. Sudden cardiac death in the young: a consensus statement on recommended practices for cardiac examination by pathologists from the Society for Cardiovascular Pathology. Cardiovasc Pathol. 2023;63:107497.

14. Mladěnka P, Applová L, Patočka J, et al. Comprehensive review of cardiovascular toxicity of drugs and related agents. Med Res Rev. 2018;38:1332-403.

15. Grassi S, Vaiano F, Dimitrova A, et al. Fatal intoxications and inherited cardiac disorders in the young: where to draw the line? Int J Legal Med. 2025;139:1081-91.

16. Kutlu E, Avci E, Acar K. Postmortem biochemistry in deaths from ischemic heart disease. J Forensic Leg Med. 2023;100:102599.

17. Isailă O, Ion OM, Luta R, et al. Postmortem immunohistochemical findings in early acute myocardial infarction: a systematic review. Int J Mol Sci. 2024;25:7625.

18. Salerno M, Cocimano G, Roccuzzo S, et al. New trends in immunohistochemical methods to estimate the time since death: a review. Diagnostics. 2022;12:2114.

19. Sarquella-Brugada G, Martínez-Barrios E, Cesar S, et al. A narrative review of inherited arrhythmogenic syndromes in young population: role of genetic diagnosis in exercise recommendations. BMJ Open Sport Exerc Med. 2024;10:e001852.

20. Martínez-barrios E, Grassi S, Brión M, et al. Molecular autopsy: twenty years of post-mortem diagnosis in sudden cardiac death. Front Med. 2023;10:1118585.

21. Sessa F. MicroRNAs in cardiovascular disease. Elsevier; 2026. pp. 1-55.

22. Sessa F, Salerno M, Esposito M, et al. New insight into mechanisms of cardiovascular diseases: an integrative analysis approach to identify TheranoMiRNAs. Int J Mol Sci. 2023;24:6781.

23. Neumann JT, De Lemos JA, Apple FS, Leong DP. Cardiovascular biomarkers for risk stratification in primary prevention. Eur Heart J. 2025;46:3823-43.

24. Rajan D, Skjelbred T, Hadberg Lynge T, Tfelt-Hansen J. Sudden cardiac death and the role of postmortem genetic testing in unexplained cases. Indian Pacing Electrophysiol J. 2025;25:441-8.

25. Srivats S, Zghyer F, Shahrori Z, et al. Sudden cardiac arrest: Limitations in risk-stratification and treatment, and the potential for digital technologies and artificial intelligence to improve prediction and outcomes. Prog Cardiovasc Dis. 2025;91:144-66.

26. Tsartsalis D, Korela D, Karlsson LO, et al. Risk and protective factors for sudden cardiac death: an umbrella review of meta-analyses. Front Cardiovasc Med. 2022;9:848021.

27. Lynge TH, Albert CM, Basso C, et al. Autopsy of all young sudden death cases is important to increase survival in family members left behind. Europace. 2024;26:euae128.

28. Bonanni F, Capodici A, Gentile F, et al. Population-based screening for conditions associated with juvenile sudden cardiac death: a systematic review and meta-analysis. Eur Heart J Qual Care Clin Outcomes. 2026;12:528-41.

29. Stiles MK, Wilde AAM, Abrams DJ, et al. 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families. J Arrhythm. 2021;37:481-534.

30. Tseng ZH, Salazar JW, Olgin JE, et al. Refining the World Health Organization definition: predicting autopsy-defined sudden arrhythmic deaths among presumed sudden cardiac deaths in the POST SCD study. Circ Arrhythm Electrophysiol. 2019;12:e007171.

31. Piccolo S, Casal M, Rossi V, et al. Ventricular arrhythmias and primary prevention of sudden cardiac death in Anderson-Fabry disease. Int J Cardiol. 2024;415:132444.

32. Dewars ER, Landstrom AP. The genetic basis of sudden cardiac death: from diagnosis to emerging genetic therapies. Annu Rev Med. 2025;76:283-99.

33. Šoša I. Forensic perspective of unintentional doping, cardiovascular health, and the role of nutrition in competitive sports. Nutrients. 2026;18:736.

34. Wan EY, Rogers AJ, Lavelle M, et al. Periprocedural management and multidisciplinary care pathways for patients with cardiac implantable electronic devices: a scientific statement from the American Heart Association. Circulation. 2024;150:e183-96.

35. Beffagna G, Sanchis-Gomar F, Ribichini F, Lippi G. Sudden cardiac arrest and death in sports: an updated overview of epidemiology, etiologies, and prevention strategies, with emphasis on inherited cardiomyopathies. Semin Thromb Hemost. 2025:Online ahead of print.

36. Sisodia U. Chain of custody: scaling the investigation to the event. In: Singh J, Sharma NR, editors. Crime scene management within forensic science. Singapore: Springer; 2022. pp. 407-18.

37. Markwerth P, Bajanowski T, Tzimas I, Dettmeyer R. Sudden cardiac death-update. Int J Legal Med. 2021;135:483-95.

38. Basso C, Stone JR. Autopsy in the era of advanced cardiovascular imaging. Eur Heart J. 2022;43:2461-8.

39. Basso C, Calabrese F, Angelini A, Carturan E, Thiene G. Classification and histological, immunohistochemical, and molecular diagnosis of inflammatory myocardial disease. Heart Fail Rev. 2012;18:673-81.

40. Banner J, Basso C, Tolkien Z, Kholova I, Michaud K, Gallagher PJ. Autopsy examination in sudden cardiac death: a current perspective on behalf of the Association for European Cardiovascular Pathology. Virchows Arch. 2020;478:687-93.

41. Basso C, Burke M, Fornes P, et al. Guidelines for autopsy investigation of sudden cardiac death. Virchows Arch. 2007;452:11-8.

42. Sabatasso S, Banz Y, Ringger R, et al. Second opinion system for sudden cardiac death cases in forensic practice. Int J Legal Med. 2020;134:1255-63.

43. Radaelli D, Westaby J, Finocchiaro G, Sinagra G, D'errico S, Sheppard MN. Sudden cardiac death with morphologically normal heart: always do toxicology. J Clin Pathol. 2024;77:645-6.

44. Arockiam AD, Saravanan PB, Singh P, Feeney AJ, Agrawal A. Exploration of spontaneous coronary artery dissection: pathophysiology, diagnosis, management, and clinical implications. Rev Cardiovasc Med. 2025;26:45172.

45. Verboova L, Nedoroscik A, Kiskova-Simkova T, et al. Atherosclerosis: a pathologist’s perspective. J Cardiovasc Dev Dis. 2026;13:85.

46. Lynge TH, Nielsen TS, Winkel BG, Tfelt-Hansen J, Banner J. Sudden cardiac death caused by myocarditis in persons aged 1-49 years: a nationwide study of 14 294 deaths in Denmark. Forensic Sci Res. 2019;4:247-56.

47. Peranantham S, Shanmugam K, Tamilselvi V. Forensic pathological context of sudden cardiac death. SSR Inst Int J Life Sci. 2024;10:6582-6.

48. Šoša I. A Meta-narrative review of channelopathies and cannabis: mechanistic, epidemiologic, and forensic insights into arrhythmia and sudden cardiac death. Int J Mol Sci. 2025;26:8635.

49. Schultheiss H, Escher F, Aleshcheva G, Wiegleb G, Baumeier C. Diagnostic and therapeutic options in myocarditis and inflammatory cardiomyopathy. Biomedicines. 2026;14:691.

50. Fadoni J, Santos A, Amorim A, Cainé L. Sudden cardiac death: the role of molecular autopsy with next-generation sequencing. Diagnostics. 2025;15:460.

51. Lucena JS. Sudden cardiac death. Forensic Sci Res. 2019;4:199-201.

52. Celeski M, Di Gioia G, Nusca A, et al. The spectrum of coronary artery disease in elite endurance athletes—a long-standing debate: state-of-the-art review. J Clin Med. 2024;13:5144.

53. Pala B, Piscione M, Cribari F, Gualtieri P, Perrone MA, Di Renzo L. A clinician-oriented approach to plaque pathology in ACS: implications for personalized cardiovascular medicine—a comprehensive review. J Pers Med. 2026;16:240.

54. Sgreva S, Alsubai SE, Bianchini E, et al. Plaques do not act alone: time to redefine coronary vulnerability from lesion to phenotype. J Clin Med. 2025;14:7568.

55. Collet C, Sakai K, Mizukami T, et al. Vascular remodeling in coronary microvascular dysfunction. JACC Cardiovasc Imaging. 2024;17:1463-76.

56. Padro T, Manfrini O, Bugiardini R, et al. ESC Working Group on Coronary Pathophysiology and Microcirculation position paper on ‘coronary microvascular dysfunction in cardiovascular disease’. Cardiovasc Res. 2020;116:741-55.

57. Rehan R, Yong A, Ng M, Weaver J, Puranik R. Coronary microvascular dysfunction: a review of recent progress and clinical implications. Front Cardiovasc Med. 2023;10:1111721.

58. Elendu C, Amaechi DC, Alakwe-Ojimba CE, et al. Understanding Sickle cell disease: causes, symptoms, and treatment options. Medicine. 2023;102:e35237.

59. Martin KC, Straathof D, Lai C, Vinters HV. Ischemic stroke in hypereosinophilic syndrome: a clinicopathologic study of two cases. Neuropathology. 2025;46:e70038.

60. Osman J, Tan SC, Lee PY, Low TY, Jamal R. Sudden cardiac death (SCD) - risk stratification and prediction with molecular biomarkers. J Biomed Sci. 2019;26:39.

61. Tabbah R, Saliba W, Abi-Saleh B. Sudden cardiac death in stable coronary artery disease: a literature review. Am Heart J Plus. 2026;61:100674.

62. Finocchiaro G, Westaby J, Sheppard MN, Papadakis M, Sharma S. Sudden cardiac death in young athletes: JACC state-of-the-art review. J Am Coll Cardiol. 2024;83:350-70.

63. Rizzo S, Carturan E, De Gaspari M, Pilichou K, Thiene G, Basso C. Update on cardiomyopathies and sudden cardiac death. Forensic Sci Res. 2019;4:202-10.

64. Zhang Y, Adamo M, Zou C, et al. Management of hypertrophic cardiomyopathy. J Cardiovasc Med. 2024;25:399-419.

65. Sclafani M, Perrotti C, Salerno L, et al. Imaging myocardial scar in hypertrophic cardiomyopathy: advances in CMR and CT. Front Cardiovasc Med. 2025;12:1649728.

66. Aguiar Rosa S, Rocha Lopes L, Fiarresga A, Ferreira RC, Mota Carmo M. Coronary microvascular dysfunction in hypertrophic cardiomyopathy: Pathophysiology, assessment, and clinical impact. Microcirculation. 2020;28:e12656.

67. Lodato V, Parlapiano G, Calì F, et al. Cardiomyopathies in children and systemic disorders when is it useful to look beyond the heart? J Cardiovasc Dev Dis. 2022;9:47.

68. Calabrese S, Cianci V, Sapienza D, et al. Postmortem diagnosis of dilated cardiomyopathy: a systematic review revisiting fundamentals. Diagnostics. 2025;15:3063.

69. Corrado D, Thiene G, Bauce B, et al. The “Padua classification” of cardiomyopathies: combining pathobiological basis and morpho-functional remodeling. Int J Cardiol. 2025;418:132571.

70. Limongelli G, Adorisio R, Baggio C, et al. Diagnosis and management of rare cardiomyopathies in adult and paediatric patients. A position paper of the Italian society of cardiology (SIC) and Italian society of paediatric cardiology (SICP). Int J Cardiol. 2022;357:55-71.

71. Siddiqi OK, Ruberg FL. Cardiac amyloidosis: an update on pathophysiology, diagnosis, and treatment. Trends Cardiovasc Med. 2018;28:10-21.

72. Kaski JP, Norrish G. Family screening in gene-elusive hypertrophic cardiomyopathy. J Am Coll Cardiol. 2023;82:1762-4.

73. Zhu W, Bian X, Lv J. From genes to clinical management: a comprehensive review of long QT syndrome pathogenesis and treatment. Heart Rhythm O2. 2024;5:573-86.

74. Van Den Heuvel L, Do J, Yeates L, Burns C, Semsarian C, Ingles J. Sudden cardiac death in the young: a qualitative study of experiences of family members with cardiogenetic evaluation. J Genet Couns. 2023;33:361-9.

75. Kumar A, Tantray J, Kosey S, Devi CH, Prajapati B. Decoding Brugada syndrome: a comprehensive analysis of pathophysiology, genetic foundations and advanced clinical management. Health Sci Rev. 2025;16:100238.

76. Aggarwal A, Stolear A, Alam MM, et al. Catecholaminergic polymorphic ventricular tachycardia: clinical characteristics, diagnostic evaluation and therapeutic strategies. J Clin Med. 2024;13:1781.

77. Modena M, Giannoni A, Aimo A, et al. Whole-exome sequencing to identify causative variants in juvenile sudden cardiac death. Hum Genomics. 2024;18:102.

78. Lasica R, Djukanovic L, Savic L, et al. Update on myocarditis: from etiology and clinical picture to modern diagnostics and methods of treatment. Diagnostics. 2023;13:3073.

79. Sozzi FB, Gherbesi E, Faggiano A, et al. Viral myocarditis: classification, diagnosis, and clinical implications. Front Cardiovasc Med. 2022;9:908663.

80. Maleszewski JJ, Banner J, de Boer H, et al. Lymphocytic myocarditis: a histopathologic definition and classification from the Society for Cardiovascular Pathology and Association for European Cardiovascular Pathology. II: surgical and autopsy specimens. Cardiovasc Pathol. 2025;78:107748.

81. Patel R, Mistry AM, Mulukutla V, Prajapati K. Cardiac sarcoidosis: a literature review of current recommendations on diagnosis and management. Cureus. 2023;15:e41451.

82. Vereckei A, Besenyi Z, Nagy V, et al. Cardiac sarcoidosis: a comprehensive clinical review. Rev Cardiovasc Med. 2024;25:37.

83. Cunha F, Teixeira-Tavares N. Drug-induced toxic myocarditis: doxorubicin once again leading to Heart Failure. Gal Clin. 2016;77:78.

84. Theetha Kariyanna P, Jayarangaiah A, Singh N, et al. Marijuana induced myocarditis: a new entity of toxic myocarditis. Am J Med Case Rep. 2018;6:169-72.

85. Falleti J, Orabona P, Municinò M, Castellaro G, Fusco G, Mansueto G. An update on myocarditis in forensic pathology. Diagnostics. 2024;14:760.

86. Castiglione V, Modena M, Aimo A, et al. Molecular autopsy of sudden cardiac death in the genomics era. Diagnostics. 2021;11:1378.

87. Fu B, Lian X, Huang H, et al. Myocardial fibrosis predicts sudden cardiac death in patients with hypertrophic cardiomyopathy after cardiac electronic device implantation: insights from cardiovascular magnetic resonance imaging. Heart Rhythm O2. 2026;7:119-29.

88. Ottaviani G, Alfonsi G, Ramos SG, Buja LM. Sudden unexpected death associated with arrhythmogenic cardiomyopathy: study of the cardiac conduction system. Diagnostics. 2021;11:1323.

89. Salzillo C, Marzullo A. Post-mortem genetic testing: role in sudden cardiac death in the young. Forensic Sci Int Genet. 2026;82:103414.

90. Burke W, Parens E, Chung WK, Berger SM, Appelbaum PS. The challenge of genetic variants of uncertain clinical significance: a narrative review. Ann Intern Med. 2022;175:994-1000.

91. Scheiper-Welling S, Tabunscik M, Gross TE, et al. Variant interpretation in molecular autopsy: a useful dilemma. Int J Legal Med. 2022;136:475-82.

92. Solomon N, Elifritz J, Adolphi NL, et al. Postmortem CT: applications in clinical and forensic medicine. Radiographics. 2025;45:e240192.

93. Michaud K, Jacobsen C, Basso C, et al. Application of postmortem imaging modalities in cases of sudden death due to cardiovascular diseases-current achievements and limitations from a pathology perspective: endorsed by the Association for European Cardiovascular Pathology and by the International Society of Forensic Radiology and Imaging. Virchows Arch. 2022;482:385-406.

94. Komura D, Ochi M, Ishikawa S. Machine learning methods for histopathological image analysis: updates in 2024. Comput Struct Biotechnol J. 2025;27:383-400.

95. Cafarelli FP, Macarini L, Cipolloni L, et al. Ex situ heart magnetic resonance imaging and angiography: feasibility study for forensic purposes. Forensic Imag. 2021;25:200442.

96. Ruder TD, Thali MJ, Hatch GM. Essentials of forensic post-mortem MR imaging in adults. Brit J Radiol. 2014;87:20130567.

97. Michaud K, Genet P, Sabatasso S, Grabherr S. Postmortem imaging as a complementary tool for the investigation of cardiac death. Forensic Sci Res. 2019;4:211-22.

98. Bertozzi G, Cafarelli FP, Ferrara M, et al. Sudden cardiac death and ex-situ post-mortem cardiac magnetic resonance imaging: a morphological study based on diagnostic correlation methodology. Diagnostics. 2022;12:218.

99. Brancato D, Treccarichi S, Bruno F, et al. NGS approaches in clinical diagnostics: from workflow to disease-specific applications. Int J Mol Sci. 2025;26:9597.

100. Orland KM, Anderson KB. Molecular autopsy for sudden cardiac death: current state and considerations. Curr Genet Med Rep. 2019;7:145-52.

101. Fellmann F, Van El CG, Charron P, et al. European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death. Eur J Hum Genet. 2019;27:1763-73.

102. Sessa F, Chisari M, Esposito M, Karaboue MAA, Salerno M, Cocimano G. Ethical, legal and social implications (ELSI) regarding forensic genetic investigations (FGIs). J Acad Ethics. 2024;23:617-37.

103. Mcguire AL, Moore Q, Majumder M, et al. The ethics of conducting molecular autopsies in cases of sudden death in the young. Genome Res. 2016;26:1165-9.

104. Hajdarpašić A, Tukker M, Rijdt WT, Mohamedhoesein S, Meijers WC, Caliskan K. Epigenetics of cardiomyopathies: the next frontier. Heart Fail Rev. 2024;30:257-70.

105. Neubauer J, Dørum G, Haas C. Exploring transcriptomic signatures in sudden unexplained death (SUD) cases. Int J Legal Med. 2025;139:1477-93.

106. Aljakna A, Fracasso T, Sabatasso S. Molecular tissue changes in early myocardial ischemia: from pathophysiology to the identification of new diagnostic markers. Int J Legal Med. 2018;132:425-38.

107. Hasselbalch RB, Kristensen JH, Strandkjær N, et al. Metabolomics of early myocardial ischemia. Metabolomics. 2023;19:33.

108. Bai H, Sun K, Wu J, et al. Proteomic and metabolomic characterization of cardiac tissue in acute myocardial ischemia injury rats. PLoS ONE. 2020;15:e0231797.

109. Sacco MA, Gualtieri S, Calanna L, Ricci P, Aquila I. Exploring the potential of proteome analysis as a promising tool for evaluation of sudden cardiac death (SCD) in forensic settings: a literature review. Int J Mol Sci. 2023;24:14351.

110. D’antonio G, Di Fazio N, Pellegrini L, et al. Immunohistochemical assessment of acute myocardial infarction: a systematic review. Int J Mol Sci. 2025;26:8901.

111. Mondello C, Ventura Spagnolo E, Cardia L, et al. Membrane attack complex in myocardial ischemia/reperfusion injury: a systematic review for post mortem applications. Diagnostics. 2020;10:898.

112. Mondello C, Cardia L, Ventura-Spagnolo E. Immunohistochemical detection of early myocardial infarction: a systematic review. Int J Legal Med. 2016;131:411-21.

113. Parisi F, Degl’innocenti S, Aytaş Ç, Pirone A, Cantile C. Morphological and immunohistochemical changes in progressive postmortem autolysis of the murine brain. Animals. 2024;14:3676.

114. Sharija S, Sasikala K, Sarathkumar A, Prabhakaran GN. Comparison of cardiac troponin in postmortem blood sample of sudden cardiac death and non-cardiac death. J Indian Acad Forensic Med. 2019;41:187.

115. Sethi P, Peiris CD. A review of catecholamine associated cardiomyopathies and channelopathies. Cureus. 2020;12:e6957.

116. Lee S, Cheong H. Factors influencing postmortem catecholamine level and its correlations with agony time and cause of death in medicolegal autopsy. J Korean Med Sci. 2023;38:e245.

117. Grassi VM, Ciasca G, Vetrugno G, Urbani A, Pascali VL, De-Giorgio F. Exploring the post-mortem interval through blood biochemistry: a preliminary case series study and review of the literature. Int J Legal Med. 2025;139:3093-102.

118. Corrado D, Zorzi A. Sudden death in athletes. Int J Cardiol. 2017;237:67-70.

119. Han J, Lalario A, Merro E, et al. Sudden cardiac death in athletes: facts and fallacies. J Cardiovasc Dev Dis. 2023;10:68.

120. Zhang S, Huang J, Wang H. Influencing factors of women’s sports participation based on self-determination theory: a systematic review and meta-analysis. Psychol Res Behav Manag. 2024;17:2953-69.

121. Wu Y, Ai M, Bardeesi ASA, et al. The forensic pathological analysis of sport-related sudden cardiac death in Southern China. Forensic Sci Res. 2017;5:47-54.

122. Egger F, Ukaj A, Hollander K. Sudden cardiac death in sports. Dtsch Z Sportmed. 2023;74:14-8.

123. Fisher AR, Bouland AJ, Zemple R, Jackson KJ, Perkins J. A novel approach to community CPR and AED outreach focused on underserved learner communities. JACEP Open. 2024;5:e13183.

124. Goldstein RD, Blair PS, Sens MA, et al. Inconsistent classification of unexplained sudden deaths in infants and children hinders surveillance, prevention and research: recommendations from The 3rd International Congress on Sudden Infant and Child Death. Forensic Sci Med Pathol. 2019;15:622-8.

125. Turillazzi E, La Rocca G, Anzalone R, et al. Heterozygous nonsense SCN5A mutation W822X explains a simultaneous sudden infant death syndrome. Virchows Arch. 2008;453:209-16.

126. Pomara C, D’errico S, Riezzo I, De Cillis GP, Fineschi V. Sudden cardiac death in a child affected by Prader-Willi syndrome. Int J Legal Med. 2005;119:153-7.

127. Sacco MA, Gualtieri S, Verrina MC, et al. A narrative overview of fatal myocarditis in infant with focus on sudden unexpected death and forensic implications. J Clin Med. 2025;14:4340.

128. Pries AM, Van Der Crabben SN, Moll HA, et al. Genetic evaluation of sudden unexpected death in infants and children. Eur J Pediatr. 2025;184:670.

129. Cottengim C, Parks S, Rhoda D, et al. Protocols, practices, and needs for investigating sudden unexpected infant deaths. Forensic Sci Med Pathol. 2019;16:91-8.

130. Bjune T, Risgaard B, Kruckow L, et al. Post-mortem toxicology in young sudden cardiac death victims: a nationwide cohort study. Europace. 2018;20:614-21.

131. Trytell A, Osekowski M, Zentner D, et al. Prevalence of illicit drug use in young patients with sudden cardiac death. Heart Rhythm. 2023;20:1349-55.

132. Stephenson L, Van Den Heuvel C, Scott T, Byard RW. Difficulties associated with the interpretation of postmortem toxicology. J Anal Toxicol. 2024;48:405-12.

133. Ripoll T, García AB, Gomila I, et al. Post-mortem toxicology in the diagnosis of sudden death in young and middle-aged victims. Eur Rev Med Pharmacol Sci. 2019;23:9135-49.

134. Wassef B, Kohansieh M, Makaryus AN. Effects of energy drinks on the cardiovascular system. World J Cardiol. 2017;9:796-806.

135. Martinez KA, Bains S, Neves R, Giudicessi JR, Bos JM, Ackerman MJ. Sudden cardiac arrest occurring in temporal proximity to consumption of energy drinks. Heart Rhythm. 2024;21:1083-8.

136. Vetter VL, Naim MY. Cardiovascular toxicity of energy drinks in youth: a call for regulation. J Pediatr. 2024;275:114224.

137. Bruce JL, Singh S, von Schwarz ER. Myocardial infarction after energy drink overconsumption in adolescents and young adults: mechanistic vulnerability in strength athletes, extreme dieters and other high-risk groups. Med Clin Case Rep J. 2026;4:1651-8.

138. Sessa F, Ministeri F, Chisari M, et al. Charged to death: energy drinks, smart drugs, and sudden cardiac death. Exp Mol Pathol. 2026;147:105068.

139. Alfsen GC, Gulczyński J, Kholová I, et al. Code of practice for medical autopsies: a minimum standard position paper for pathology departments performing medical (hospital) autopsies in adults. Virchows Arch. 2021;480:509-17.

140. La Vigne N. Death investigation: a guide for the scene investigator. Washington, 2024. Available from: https://nij.ojp.gov/library/publications/death-investigation-guide-scene-investigator-2024 [Last accessed on 14 Sep 2026].

141. Michaud K, Basso C, de Boer HH, et al. Ischemic and non-ischemic myocardial injuries at autopsy- an overview for forensic pathologists. Int J Legal Med. 2025;139:1579-96.

142. Tanz LJ, Miller KD, Dinwiddie AT, et al. Drug overdose deaths involving stimulants - United States, January 2018–June 2024. MMWR Morb Mortal Wkly Rep. 2025;74:491-9.

143. Schumann JL, Hlela MBKM, Oliverio S, Bugeja L. Forensic epidemiology: bridging public health and legal investigations to address modern challenges. WIREs Forensic Sci. 2025;7:e70003.

144. Radu I, Farcas AO, Nyulas V, Radu CC, Brinzaniuc K. Sudden cardiac death-etiology, risk factors and demographic characteristics: an extensive study of 1618 forensic autopsies. Diseases. 2024;12:168.

145. Votýpka P, Krebsová A, Norambuena-Poustková P, et al. Post-mortem genetic testing in sudden cardiac death and genetic screening of relatives at risk: lessons learned from a Czech pilot multidisciplinary study. Int J Legal Med. 2023;137:1787-801.

146. Bezzina CR, Lahrouchi N, Priori SG. Genetics of sudden cardiac death. Circ Res. 2015;116:1919-36.

147. Priya A, Gupta SK, Ashok C, Paswan MK. Sudden cardiac death and its histopathological findings in autopsy cases in Jharkhand. J Family Med Prim Care. 2025;14:1058-63.

148. Buonpane A, De Caterina AR, Trimarchi G, et al. Unveiling the causes of acute and non-acute myocardial ischemic syndromes: the role of optical coherence tomography. Medicina. 2025;61:1218.

149. Akdemir T, Az A, Doğan Y, Akdemir E. Sudden death in the emergency department: a comprehensive 8-year study integrating clinical and autopsy data. Turk J Emerg Med. 2025;305:12.

150. Simmons KM, Mcisaac SM, Ohle R. Impact of community-based interventions on out-of-hospital cardiac arrest outcomes: a systematic review and meta-analysis. Sci Rep. 2023;13:10231.

151. Gutiérrez-Hurtado IA, García-Acéves ME, Puga-Carrillo Y, et al. Past, present and future perspectives of forensic genetics. Biomolecules. 2025;15:713.

152. Le Goff D, Perraud G, Aujoulat P, et al. Screening for cardiovascular risk in the general population: the SPICES implementation survey. Front Med. 2023;9:1058090.

153. Yang Z, Zhao JV, Qi Y, Deng X, Ji Z, Liu J. A translational framework of genoproteomic studies for cardiovascular drug discovery. NPJ Cardiovasc Health. 2024;1:12.

154. Nurmohamed NS, Belo Pereira JP, Hoogeveen RM, et al. Targeted proteomics improves cardiovascular risk prediction in secondary prevention. Eur Heart J. 2022;43:1569-77.

155. Ribeiro S, Coelho L, Puentes K, et al. Teste genético post mortem, o diagnóstico clínico não se esgota com a morte do doente. Rev Port Cardiol. 2019;38:503-9.

156. Marey I, Fressart V, Rambaud C, et al. Clinical impact of post-mortem genetic testing in cardiac death and cardiomyopathy. Open Med. 2020;15:435-46.

157. Campuzano Larrea O, Fernandez A, Mademont I, et al. P1694 natural and undetermined sudden death: value of post-mortem genetic investigation. Eur Heart J. 2017;38:1694.

158. Sanchez O, Campuzano O, Fernández-Falgueras A, et al. Natural and undetermined sudden death: value of post-mortem genetic investigation. PLoS ONE. 2016;11:e0167358.

159. Wang S, Du J, Shen Q, Haas C, Neubauer J. Interpretation of molecular autopsy findings in 45 sudden unexplained death cases: from coding region to untranslated region. Int J Legal Med. 2024;139:15-25.

160. Latimer R, MacLeod H, Dellefave-Castillo L, Macaya D, Hart TR. Postmortem genetic testing is an increasingly utilized tool in death investigation. Acad Forensic Pathol. 2022;12:129-39.

161. Wang W, Bursac Z, Hu N. Joint modeling of longitudinal and survival data in public health and biomedical research: a systematic review. Int J Environ Res Public Health. 2026;23:492.

162. Macleod H, Buczkowski E, Faulkner M, Felzke K, Burns KM. What has the sudden unexpected infant death and sudden death in the young case registry learned about consenting families for DNA banking and/or genomic research? Am J Forensic Med Pathol. 2024;45:297-8.

163. Sundström E, Jensen SM, Diamant U, Rydberg A. Implantable cardioverter defibrillator treatment in long QT syndrome patients: a national study on adherence to international guidelines. Scand Cardiovasc J. 2016;51:88-94.

164. Sessa F, Anna V, Messina G, et al. Heart rate variability as predictive factor for sudden cardiac death. Aging. 2018;10:166-77.

165. Holm PH, Jensen THL, Westaby J, et al. Quantitative histological insights into sudden arrhythmic death syndrome: findings from a forensic autopsy cohort. APMIS. 2026;134:e70169.

166. Kundur S, Malik A, Mizori R, Sivalokanathan S. Exploring the genetic architecture of myocarditis and inherited cardiomyopathies. Cardiogenetics. 2026;16:4.

167. Fishman GI, Chugh SS, Dimarco JP, et al. Sudden cardiac death prediction and prevention: report from a national heart, lung, and blood institute and heart rhythm society workshop. Circulation. 2010;122:2335-48.

168. Buja LM. Pathobiology of myocardial and cardiomyocyte injury in ischemic heart disease: Perspective from seventy years of cell injury research. Exp Mol Pathol. 2024;140:104944.

169. Kurata A. Strategy for postmortem diagnosis of myocardial infarction. Virchows Arch. 2019;476:177-8.

170. Netala VR, Teertam SK, Li H, Zhang Z. A comprehensive review of cardiovascular disease management: cardiac biomarkers, imaging modalities, pharmacotherapy, surgical interventions, and herbal remedies. Cells. 2024;13:1471.

171. Coll M, Alcalde M, Fernández-Falgueras A, et al. Value of molecular autopsy in suspected sudden cardiac death in the young. J Mol Diagn. 2025;27:859-68.

172. Huynh CD. Artificial intelligence and the evolution of pathology: scaling from digital diagnostics to multimodal precision medicine. Intell Based Med. 2026;14:100386.

173. Alafer F. Emerging imaging technologies in forensic medicine: a systematic review of innovations, ethical challenges, and future directions. Diagnostics. 2025;15:1410.

174. Ramatsokotla S, Soul B, Duah E, et al. Evidence of point-of-care diagnostics in forensic death investigations: a scoping review. J Forensic Leg Med. 2026;118:103086.

175. Ben Ali W, Pesaranghader A, Avram R, et al. Implementing machine learning in interventional cardiology: the benefits are worth the trouble. Front Cardiovasc Med. 2021;8:711401.

176. Kruse J, Mueller R, Aghdassi AA, Lerch MM, Salloch S. Genetic testing for rare diseases: a systematic review of ethical aspects. Front Genet. 2022;12:701988.

177. Wilhelm M, Bolliger SA, Bartsch C, et al. Sudden cardiac death in forensic medicine - Swiss recommendations for a multidisciplinary approach. Swiss Med Wkly. 2015;145:w14129.

178. Marijon E, Narayanan K, Smith K, et al. The lancet commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action. Lancet. 2023;402:883-936.

179. Ongesa TN, Ugwu OP, Ugwu CN, et al. Optimizing emergency response systems in urban health crises: a project management approach to public health preparedness and response. Medicine. 2025;104:e41279.

180. Ye H, Wang K, Sang W, et al. Multi-omics in cardiac arrest: a systematic review. Resusc Plus. 2026;27:101170.

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