fig2

Figure 2. There were no significant long-term benefits in left ventricular systolic function. (A) There were no differences in left ventricular ejection fraction (LVEF) or fractional shortening (FS) on postoperative day 3. (B) There were no differences in LVEF on postoperative day 7, but the FS of IM-EV was significantly greater than that of IV-EV (P = 0.0038). (C) On postoperative day 28, there were no differences in either LVEF or FS; IM-C, IM control injection group (n = 8); IM-EV, IM extracellular vesicles injection group (n = 9); IV-C, IV control injection group (n = 8); IV-EV, IV extracellular vesicle injection group (n = 8). The Shapiro-Wilk test was used to determine that the data were non-parametric. Then, the Kruskal-Wallis test was performed, as well as the post-hoc Dunn’s test when appropriate. The median value of each group is displayed in color on the violin plot of each group.