fig1

Figure 1. Canagliflozin improves cardiac systolic and diastolic functional parameters compared to sitagliptin in swine with chronic myocardial ischemia. Cardiac functional measurements of stroke volume (SV), stroke work (SW), cardiac output (CO), and coefficient of LV stiffness are shown in swine treated with canagliflozin (CANA, n = 8), sitagliptin (SIT, n = 5), or vehicle with no drug (CON, n = 8). *signifies a P value of less than 0.05. **signifies a P value of less than 0.01.