fig1

Figure 1. Schematic representation of main cellular sources of ROS activated in heart disease and the antioxidant counterpart. ROS: reactive oxygen species; AngII: angiotensin II; ET-1: endothelin-1; Ox: Oxidase; NOS: nitric oxide synthase; NADPH: nicotinamide adenine dinucleotide phosphate; SOD: superoxide dismutase; GSHPx: glutathione peroxidase; CAT: catalase