1. Organization WH. World malaria report 2019. 2019. Available from [Last accessed on 6 May 2020].

2. Murray CJL, Rosenfeld LC, Lim SS, Andrews KG, Foreman KJ, et al. Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet 2012;379:413-31.

3. Bangirana P, Opoka RO, Boivin MJ, Idro R, Hodges JS, et al. Severe malarial anemia is associated with long-term neurocognitive impairment. Clin Infect Dis 2014;59:336-44.

4. Storm J, Craig AG. Pathogenesis of cerebral malaria--inflammation and cytoadherence. Front Cell Infect Microbiol 2014;4:100.

5. Organization WH. Management of severe malaria: a practical handbook.; 2012. Available from [Last accessed on 6 May 2020].

6. Jakeman GN, Saul A, Hogarth WL, Collins WE. Anaemia of acute malaria infections in non-immune patients primarily results from destruction of uninfected erythrocytes. Parasitology 1999;119:127-33.

7. Lamikanra AA, Brown D, Potocnik A, Casals-Pascual C, Langhorne J, et al. Malarial anemia: of mice and men. Blood 2007;110:18-28.

8. Vainieri ML, Blagborough AM, MacLean AL, Haltalli MLR, Ruivo N, et al. Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points. Open Biol 2016;6:160038.

9. Razakandrainibe R, Combes V, Grau GE, Jambou R. Crossing the wall: the opening of endothelial cell junctions during infectious diseases. Int J Biochem Cell Biol 2013;45:1165-73.

10. Dorovini-Zis K, Schmidt K, Huynh H, Fu W, Whitten RO, et al. The neuropathology of fatal cerebral malaria in malawian children. Am J Pathol 2011;178:2146-58.

11. Taylor TE, Fu WJ, Carr RA, Whitten RO, Mueller JS, et al. Differentiating the pathologies of cerebral malaria by postmortem parasite counts. Nat Med 2004;10:143-5.

12. Ponsford MJ, Medana IM, Prapansilp P, Hien TT, Lee SJ, et al. Sequestration and microvascular congestion are associated with coma in human cerebral malaria. J Infect Dis 2012;205:663-71.

13. Combes V, Guillemin GJ, Chan-Ling T, Hunt NH, Grau GER. The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. Trends Parasitol 2012;28:311-9.

14. Dunst J, Kamena F, Matuschewski K. Cytokines and chemokines in cerebral malaria pathogenesis. Front Cell Infect Microbiol 2017;7:324.

15. Wassmer SC, Grau GER. Platelets as pathogenetic effectors and killer cells in cerebral malaria. Expert Rev Hematol 2016;9:515-7.

16. Chimalizeni Y, Kawaza K, Taylor T, Molyneux M. The platelet count in cerebral malaria, is it useful to the clinician? Am J Trop Med Hyg 2010;83:48-50.

17. Gérardin P, Rogier C, Ka AS, Jouvencel P, Brousse V, et al. Prognostic value of thrombocytopenia in African children with falciparum malaria. Am J Trop Med Hyg 2002;66:686-91.

18. Grau GE, Mackenzie CD, Carr RA, Redard M, Pizzolato G, et al. Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria. J Infect Dis 2003;187:461-6.

19. Wassmer SC, Taylor T, Maclennan CA, Kanjala M, Mukaka M, et al. Platelet-induced clumping of Plasmodium falciparum-infected erythrocytes from Malawian patients with cerebral malaria-possible modulation in vivo by thrombocytopenia. J Infect Dis 2008;197:72-8.

20. Barbier M, Faille D, Loriod B, Textoris J, Camus C, et al. Platelets alter gene expression profile in human brain endothelial cells in an in vitro model of cerebral malaria. PLoS One 2011;6:e19651.

21. Wassmer SC, Combes V, Candal FJ, Juhan-Vague I, Grau GE. Platelets potentiate brain endothelial alterations induced by Plasmodium falciparum. Infect Immun 2006;74:645-53.

22. McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, et al. Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum. Science 2012;338:1348-51.

23. Peyron F, Polack B, Lamotte D, Kolodie L, Ambroise-Thomas P. Plasmodium falciparum growth inhibition by human platelets in vitro. Parasitology 1989;99:317-22.

24. Aggrey AA, Srivastava K, Ture S, Field DJ, Morrell CN. Platelet induction of the acute-phase response is protective in murine experimental cerebral malaria. J Immunol 2013;190:4685-91.

25. Medana IM, Turner GDH. Human cerebral malaria and the blood-brain barrier. Int J Parasitol 2006;36:555-68.

26. Medana IM, Day NP, Hien TT, Mai NTH, Bethell D, et al. Axonal injury in cerebral malaria. Am J Pathol 2002;160:655-66.

27. Adams S, Brown H, Turner G. Breaking down the blood-brain barrier: signaling a path to cerebral malaria? Trends Parasitol 2002;18:360-6.

28. Beare NAV, Harding SP, Taylor TE, Lewallen S, Molyneux ME. Perfusion abnormalities in children with cerebral malaria and malarial retinopathy. J Infect Dis 2009;199:263-71.

29. Kampondeni SD, Birbeck GL, Seydel KB, Beare NA, Glover SJ, et al. Noninvasive measures of brain edema predict outcome in pediatric cerebral malaria. Surg Neurol Int 2018;9:53.

30. Seydel KB, Kampondeni SD, Valim C, Potchen MJ, Milner DA, et al. Brain swelling and death in children with cerebral malaria. N Engl J Med 2015;372:1126-37.

31. Schindler SM, Little JP, Klegeris A. Microparticles: a new perspective in central nervous system disorders. Biomed Res Int 2014;2014:756327.

32. Schofield L, Grau GE. Immunological processes in malaria pathogenesis. Nat Rev Immunol 2005;5:722-35.

33. Doyle LM, Wang MZ. Overview of extracellular vesicles, their origin, composition, purpose, and methods for exosome isolation and analysis. Cells 2019;8:727.

34. Mantel PY, Marti M. The role of extracellular vesicles in Plasmodium and other protozoan parasites. Cell Microbiol 2014;16:344-54.

35. Torrecilhas AC, Schumacher RI, Alves MJM, Colli W. Vesicles as carriers of virulence factors in parasitic protozoan diseases. Microbes Infect 2012;14:1465-74.

36. Combes V, Taylor TE, Juhan-Vague I, Mège JL, Mwenechanya J, et al. Circulating endothelial microparticles in malawian children with severe falciparum malaria complicated with coma. JAMA 2004;291:2542-4.

37. Campos FMF, Franklin BS, Teixeira-Carvalho A, Filho ALS, de Paula SCO, et al. Augmented plasma microparticles during acute Plasmodium vivax infection. Malar J 2010;9:327.

38. Nantakomol D, Dondorp AM, Krudsood S, Udomsangpetch R, Pattanapanyasat K, et al. Circulating red cell-derived microparticles in human malaria. J Infect Dis 2011;203:700-6.

39. Pankoui Mfonkeu JB, Gouado I, Fotso Kuaté H, Zambou O, Amvam Zollo PH, et al. Elevated cell-specific microparticles are a biological marker for cerebral dysfunctions in human severe malaria. PLoS One 2010;5:e13415.

40. Martin-Jaular L, Nakayasu ES, Ferrer M, Almeida IC, Del Portillo HA. Exosomes from Plasmodium yoelii-infected reticulocytes protect mice from lethal infections. PLoS One 2011;6:e26588.

41. Bridges DJ, Bunn J, van Mourik JA, Grau G, Preston RJS, et al. Rapid activation of endothelial cells enables Plasmodium falciparum adhesion to platelet-decorated von Willebrand factor strings. Blood 2010;115:1472-4.

42. El-Assaad F, Wheway J, Mitchell AJ, Lou J, Hunt NH, et al. Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infect Immun 2013;81:3984-91.

43. Jambou R, El-Assaad F, Combes V, Grau GE. In vitro culture of Plasmodium berghei-ANKA maintains infectivity of mouse erythrocytes inducing cerebral malaria. Malar J 2011;10:346.

44. Khaw LT, Ball HJ, Golenser J, Combes V, Grau GE, et al. Endothelial cells potentiate interferon-γ production in a novel tripartite culture model of human cerebral malaria. PLoS One 2013;8:e69521.

45. Wassmer SC, Lépolard C, Traoré B, Pouvelle B, Gysin J, et al. Platelets reorient Plasmodium falciparum-infected erythrocyte cytoadhesion to activated endothelial cells. J Infect Dis 2004;189:180-9.

46. Canfield SG, Stebbins MJ, Morales BS, Asai SW, Vatine GD, et al. An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells. J Neurochem 2017;140:874-88.

47. Cho H, Seo JH, Wong KHK, Terasaki Y, Park J, et al. Three-dimensional blood-brain barrier model for in vitro studies of neurovascular pathology. Sci Rep 2015;5:15222.

48. Helms HC, Abbott NJ, Burek M, Cecchelli R, Couraud PO, et al. In vitro models of the blood-brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use. J Cereb Blood Flow Metab 2016;36:862-90.

49. Faille D, Combes V, Mitchell AJ, Fontaine A, Juhan-Vague I, et al. Platelet microparticles: a new player in malaria parasite cytoadherence to human brain endothelium. FASEB J 2009;23:3449-58.

50. Wassmer SC, Combes V, Grau GER. Platelets and microparticles in cerebral malaria: the unusual suspects. Drug Discov Today Dis Mechanisms 2011;8:e15-23.

51. Sampaio NG, Emery SJ, Garnham AL, Tan QY, Sisquella X, et al. Extracellular vesicles from early stage Plasmodium falciparum-infected red blood cells contain PfEMP1 and induce transcriptional changes in human monocytes. Cell Microbiol 2018;20:e12822.

52. Mantel PY, Hjelmqvist D, Walch M, Kharoubi-Hess S, Nilsson S, et al. Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria. Nat Commun 2016;7:12727.

53. Wang Z, Xi J, Hao X, Deng W, Liu J, et al. Red blood cells release microparticles containing human argonaute 2 and miRNAs to target genes of Plasmodium falciparum. Emerg Microbes Infect 2017;6:e75.

54. Couper KN, Barnes T, Hafalla JCR, Combes V, Ryffel B, et al. Parasite-derived plasma microparticles contribute significantly to malaria infection-induced inflammation through potent macrophage stimulation. PLoS Pathog 2010;6:e1000744.

55. Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, et al. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe 2013;13:521-34.

56. Sisquella X, Ofir-Birin Y, Pimentel MA, Cheng L, Abou Karam P, et al. Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors. Nat Commun 2017;8:1985.

57. Yu X, Cai B, Wang M, Tan P, Ding X, et al. Cross-regulation of two type i interferon signaling pathways in plasmacytoid dendritic cells controls anti-malaria immunity and host mortality. Immunity 2016;45:1093-107.

58. Demarta-Gatsi C, Rivkin A, Di Bartolo V, Peronet R, Ding S, et al. Histamine releasing factor and elongation factor 1 alpha secreted via malaria parasites extracellular vesicles promote immune evasion by inhibiting specific T cell responses. Cell Microbiol 2019;21:e13021.

59. Regev-Rudzki N, Wilson DW, Carvalho TG, Sisquella X, Coleman BM, et al. Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles. Cell 2013;153:1120-33.

60. Wheway J, Latham SL, Combes V, Grau GER. Endothelial microparticles interact with and support the proliferation of T cells. J Immunol 2014;193:3378-87.

61. Gasser O, Schifferli JA. Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis. Blood 2004;104:2543-8.

62. Rhys HI, Dell’Accio F, Pitzalis C, Moore A, Norling LV, et al. Neutrophil microvesicles from healthy control and rheumatoid arthritis patients prevent the inflammatory activation of macrophages. EBioMedicine 2018;29:60-9.

63. Wen B, Combes V, Bonhoure A, Weksler BB, Couraud PO, et al. Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses. PLoS One 2014;9:e91597.

64. Riggle BA, Manglani M, Maric D, Johnson KR, Lee MH, et al. CD8+ T cells target cerebrovasculature in children with cerebral malaria. J Clin Invest 2020;130:1128-38.

65. Poh CM, Howland SW, Grotenbreg GM, Rénia L. Damage to the blood-brain barrier during experimental cerebral malaria results from synergistic effects of CD8+ T cells with different specificities. Infect Immun 2014;82:4854-64.

66. Swanson PA, Hart GT, Russo MV, Nayak D, Yazew T, et al. CD8+ T cells induce fatal brainstem pathology during cerebral malaria via luminal antigen-specific engagement of brain vasculature. PLoS Pathog 2016;12:e1006022.

67. Combes V, Souza JBD, Rénia L, Hunt NH, Grau GE. Cerebral malaria: which parasite? Which model? Drug Discov Today Dis Models 2005;2:141-7.

68. Craig AG, Grau GE, Janse C, Kazura JW, Milner D, et al. The role of animal models for research on severe malaria. PLoS Pathog 2012;8:e1002401.

69. de Souza JB, Hafalla JCR, Riley EM, Couper KN. Cerebral malaria: why experimental murine models are required to understand the pathogenesis of disease. Parasitology 2010;137:755-72.

70. El-Assaad F, Combes V, Grau GE. Experimental models of microvascular immunopathology: the example of cerebral malaria. J Neuroinfect Dis 2014;5.

71. Riley EM, Couper KN, Helmby H, Hafalla JCR, de Souza JB, et al. Neuropathogenesis of human and murine malaria. Trends Parasitol 2010;26:277-8.

72. Amante FH, Stanley AC, Randall LM, Zhou Y, Haque A, et al. A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria. Am J Pathol 2007;171:548-59.

73. Claser C, Malleret B, Gun SY, Wong AYW, Chang ZW, et al. CD8+ T cells and IFN-γ mediate the time-dependent accumulation of infected red blood cells in deep organs during experimental cerebral malaria. PLoS One 2011;6:e18720.

74. Franke-Fayard B, Janse CJ, Cunha-Rodrigues M, Ramesar J, Büscher P, et al. Murine malaria parasite sequestration: CD36 is the major receptor, but cerebral pathology is unlinked to sequestration. Proc Natl Acad Sci U S A 2005;102:11468-73.

75. Strangward P, Haley MJ, Shaw TN, Schwartz JM, Greig R, et al. A quantitative brain map of experimental cerebral malaria pathology. PLoS Pathog 2017;13:e1006267.

76. Combes V, Coltel N, Alibert M, van Eck M, Raymond C, et al. ABCA1 gene deletion protects against cerebral malaria: potential pathogenic role of microparticles in neuropathology. Am J Pathol 2005;166:295-302.

77. El-Assaad F, Wheway J, Hunt NH, Grau GER, Combes V. Production, fate and pathogenicity of plasma microparticles in murine cerebral malaria. PLoS Pathog 2014;10:e1003839.

78. Penet MF, Abou-Hamdan M, Coltel N, Cornille E, Grau GE, et al. Protection against cerebral malaria by the low-molecular-weight thiol pantethine. Proc Natl Acad Sci U S A 2008;105:1321-6.

79. Kuhn SM, McCarthy AE. Paediatric malaria: what do paediatricians need to know? Paediatr Child Health 2006;11:349-54.

80. White NJ, Pukrittayakamee S, Hien TT, Faiz MA, Mokuolu OA, et al. Malaria. Lancet 2014;383:723-35.

81. Shrivastava SK, Dalko E, Delcroix-Genete D, Herbert F, Cazenave PA, et al. Uptake of parasite-derived vesicles by astrocytes and microglial phagocytosis of infected erythrocytes may drive neuroinflammation in cerebral malaria. Glia 2017;65:75-92.

82. Martín-Jaular L, de Menezes-Neto A, Monguió-Tortajada M, Elizalde-Torrent A, Díaz-Varela M, et al. Spleen-dependent immune protection elicited by CpG adjuvanted reticulocyte-derived exosomes from malaria infection is associated with changes in T cell subsets’ distribution. Front Cell Dev Biol 2016;4:131.

83. Nantakomol D, Chimma P, Day NP, Dondorp AM, Combes V, et al. Quantitation of cell-derived microparticles in plasma using flow rate based calibration. Southeast Asian J Trop Med Public Health 2008;39:146-53.

84. Babatunde KA, Yesodha Subramanian B, Ahouidi AD, Martinez Murillo P, Walch M, et al. Role of extracellular vesicles in cellular cross talk in malaria. Front Immunol 2020;11:22.

85. Sahu PK, Satpathi S, Behera PK, Mishra SK, Mohanty S, et al. Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches. Front Cell Infect Microbiol 2015;5:75.

86. Varo R, Crowley VM, Sitoe A, Madrid L, Serghides L, et al. Adjunctive therapy for severe malaria: a review and critical appraisal. Malar J 2018;17:47.

87. Adukpo S, Kusi KA, Ofori MF, Tetteh JKA, Amoako-Sakyi D, et al. High plasma levels of soluble intercellular adhesion molecule (ICAM)-1 are associated with cerebral malaria. PLoS One 2013;8:e84181.

88. Casals-Pascual C, Idro R, Gicheru N, Gwer S, Kitsao B, et al. High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria. Proc Natl Acad Sci U S A 2008;105:2634-9.

89. Conroy AL, Lafferty EI, Lovegrove FE, Krudsood S, Tangpukdee N, et al. Whole blood angiopoietin-1 and -2 levels discriminate cerebral and severe (non-cerebral) malaria from uncomplicated malaria. Malar J 2009;8:295.

90. Thakur K, Vareta J, Carson K, Taylor T, Sullivan D. Performance of cerebrospinal fluid (CSF) plasmodium falciparum histidine-rich protein-2 (pfHRP-2) in prediction of death in cerebral malaria (I10-2.005) 2014. Available from [Last accessed on 6 May 2020].

91. Antwi-Baffour S, Malibha-Pinchbeck M, Stratton D, Jorfi S, Lange S, et al. Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets. J Extracell Vesicles 2020;9:1697124.

92. Hede MS, Fjelstrup S, Lötsch F, Zoleko RM, Klicpera A, et al. Detection of the malaria causing plasmodium parasite in saliva from infected patients using topoisomerase I activity as a biomarker. Sci Rep 2018;8:4122.

93. Krampa FD, Aniweh Y, Awandare GA, Kanyong P. Recent progress in the development of diagnostic tests for malaria. Diagnostics (Basel) 2017;7:54.

94. Choi DS, Kim DK, Kim YK, Gho YS. Proteomics, transcriptomics and lipidomics of exosomes and ectosomes. Proteomics 2013;13:1554-71.

95. Abdi A, Yu L, Goulding D, Rono MK, Bejon P, et al. Proteomic analysis of extracellular vesicles from a Plasmodium falciparum Kenyan clinical isolate defines a core parasite secretome. [version 2; peer review: 2 approved, 1 approved with reservations]. Wellcome Open Res 2017;2:50.

96. Tiberti N, Latham SL, Bush S, Cohen A, Opoka RO, et al. Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content. Sci Rep 2016;6:37871.

97. Antwi-Baffour S, Adjei JK, Agyemang-Yeboah F, Annani-Akollor M, Kyeremeh R, et al. Proteomic analysis of microparticles isolated from malaria positive blood samples. Proteome Sci 2016;15:5.

98. Gualdrón-López M, Flannery EL, Kangwanrangsan N, Chuenchob V, Fernandez-Orth D, et al. Characterization of plasmodium vivax proteins in plasma-derived exosomes from malaria-infected liver-chimeric humanized Mice. Front Microbiol 2018;9:1271.

99. Hanna J, Hossain GS, Kocerha J. The Potential for microRNA therapeutics and clinical research. Front Genet 2019;10:478.

100. Saliminejad K, Khorram Khorshid HR, Soleymani Fard S, Ghaffari SH. An overview of microRNAs: biology, functions, therapeutics, and analysis methods. J Cell Physiol 2019;234:5451-65.

101. Chen SY, Wang Y, Telen MJ, Chi JT. The genomic analysis of erythrocyte microRNA expression in sickle cell diseases. PLoS One 2008;3:e2360.

102. Chen X, Ba Y, Ma L, Cai X, Yin Y, et al. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 2008;18:997-1006.

103. Hammond SM. An overview of microRNAs. Adv Drug Deliv Rev 2015;87:3-14.

104. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci U S A 2008;105:10513-8.

105. Reid G, Kirschner MB, van Zandwijk N. Circulating microRNAs: association with disease and potential use as biomarkers. Crit Rev Oncol Hematol 2011;80:193-208.

106. Wang W, Li R, Meng M, Wei C, Xie Y, et al. MicroRNA profiling of CD3+ CD56+ cytokine-induced killer cells. Sci Rep 2015;5:9571.

107. Babatunde KA, Mbagwu S, Hernández-Castañeda MA, Adapa SR, Walch M, et al. Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles. Sci Rep 2018;8:884.

108. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-97.

109. Wang J, Sen S. MicroRNA functional network in pancreatic cancer: from biology to biomarkers of disease. J Biosci 2011;36:481-91.

110. Chen X, Jin Y, Feng Y. Evaluation of plasma extracellular vesicle microRNA signatures for lung adenocarcinoma and granuloma with monte-carlo feature selection method. Front Genet 2019;10:367.

111. Sartori MT, Della Puppa A, Ballin A, Saggiorato G, Bernardi D, et al. Prothrombotic state in glioblastoma multiforme: an evaluation of the procoagulant activity of circulating microparticles. J Neurooncol 2011;104:225-31.

112. Zwicker JI, Liebman HA, Neuberg D, Lacroix R, Bauer KA, et al. Tumor-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res 2009;15:6830-40.

113. da Silva EFR, Fonseca FAH, França CN, Ferreira PRA, Izar MCO, et al. Imbalance between endothelial progenitors cells and microparticles in HIV-infected patients naive for antiretroviral therapy. AIDS 2011;25:1595-601.

114. Pelletier F, Garnache-Ottou F, Angelot F, Biichlé S, Vidal C, et al. Increased levels of circulating endothelial-derived microparticles and small-size platelet-derived microparticles in psoriasis. J Invest Dermatol 2011;131:1573-6.

115. Stępień E, Stankiewicz E, Zalewski J, Godlewski J, Zmudka K, et al. Number of microparticles generated during acute myocardial infarction and stable angina correlates with platelet activation. Arch Med Res 2012;43:31-5.

116. Xue S, Cai X, Li W, Zhang Z, Dong W, et al. Elevated plasma endothelial microparticles in Alzheimer’s disease. Dement Geriatr Cogn Disord 2012;34:174-80.

117. Bondar G, Xu W, Elashoff D, Li X, Faure-Kumar E, et al. Comparing NGS and NanoString platforms in peripheral blood mononuclear cell transcriptome profiling for advanced heart failure biomarker development. J Biol Methods 2020;7:e123.

118. Manzano-Román R, Siles-Lucas M. MicroRNAs in parasitic diseases: potential for diagnosis and targeting. Mol Biochem Parasitol 2012;186:81-6.

119. Eichenberger RM, Talukder MH, Field MA, Wangchuk P, Giacomin P, et al. Characterization of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host-parasite communication. J Extracell Vesicles 2018;7:1428004.

120. Eichenberger RM, Ryan S, Jones L, Buitrago G, Polster R, et al. Hookworm secreted extracellular vesicles interact with host cells and prevent inducible colitis in mice. Front Immunol 2018;9:850.

121. Xue X, Zhang Q, Huang Y, Feng L, Pan W. No miRNA were found in Plasmodium and the ones identified in erythrocytes could not be correlated with infection. Malar J 2008;7:47.

122. Chamnanchanunt S, Kuroki C, Desakorn V, Enomoto M, Thanachartwet V, et al. Downregulation of plasma miR-451 and miR-16 in Plasmodium vivax infection. Exp Parasitol 2015;155:19-25.

123. Capuccini B, Lin J, Talavera-López C, Khan SM, Sodenkamp J, et al. Transcriptomic profiling of microglia reveals signatures of cell activation and immune response, during experimental cerebral malaria. Sci Rep 2016;6:39258.

124. El-Assaad F, Hempel C, Combes V, Mitchell AJ, Ball HJ, et al. Differential microRNA expression in experimental cerebral and noncerebral malaria. Infect Immun 2011;79:2379-84.

125. Lin JW, Sodenkamp J, Cunningham D, Deroost K, Tshitenge TC, et al. Signatures of malaria-associated pathology revealed by high-resolution whole-blood transcriptomics in a rodent model of malaria. Sci Rep 2017;7:41722.

126. Cohen A, Zinger A, Tiberti N, Grau GER, Combes V. Differential plasma microvesicle and brain profiles of microRNA in experimental cerebral malaria. Malar J 2018;17:192.

127. Verweij FJ, Hyenne V, Van Niel G, Goetz JG. Extracellular vesicles: catching the light in zebrafish. Trends Cell Biol 2019;29:770-6.

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