fig2

Figure 2. Process of Wallerian degeneration after peripheral nerve injury (A) intact nerve, prior to nerve injury, location of injury noted; (B) post-injury Wallerian degeneration of the nerve distal to the injury, with traumatic degeneration up to the first node of Ranvier in the nerve stump proximal to the injury; (C) axonal sprouting from the nerve proximal to the injury, where the growth cone extends down basal lamina of the endoneurial tubes; and (D) nerve regeneration complete, with connection established with distal target organ.