All Articles

Bracing for the storm: emerging resistance mechanisms to KRAS inhibitors in pancreatic cancer and strategies to overcome them

Mechanistic roles and clinical applications of tertiary lymphoid structures in colorectal cancer drug resistance

An epithelial-mesenchymal transition-related gene signature predicts prognosis, immune infiltration, and drug sensitivity in colorectal cancer

Deep spatial proteomics reveals a suppressive immune niche linked to immune evasion in renal cell carcinoma

Paired single cell analysis reveals chemotherapy resistance in osteosarcoma

Immunotherapy resistance and strategies in malignant pleural mesothelioma

Novel anti-tumor strategies: targeting the crosstalk between cancer stem cells and cancer-associated fibroblasts to resist drug resistance

Targeting tumor-draining lymph node to overcome resistance to cancer immunotherapy: an update

ROS1 mutations promote an immunosuppressive tumor microenvironment via MYC to confer immune evasion in head and neck cancer

Lactylation: a novel driver of drug resistance in the tumor microenvironment

Interactions between tumor microenvironment and resistance to transarterial and systemic treatments for HCC

Integrated multi-omics profiling of immune microenvironment and drug resistance signatures for precision prognosis in prostate cancer

ZEB2 upregulation modulates the polarization of TAMs toward the immunosuppressive state in EGFR-TKI-resistant NSCLC

Tumor microenvironment-driven resistance to immunotherapy in non-small cell lung cancer: strategies for Cold-to-Hot tumor transformation

The genetic architecture of bone metastases: unveiling the role of epigenetic and genetic modifications in drug resistance

Sophisticated roles of tumor microenvironment in resistance to immune checkpoint blockade therapy in hepatocellular carcinoma

Exploring YAP1-related TIME in SCLC: implications for survival and treatment response to immuno-chemotherapy

Metabolic crossroads: unravelling immune cell dynamics in gastrointestinal cancer drug resistance