fig5
From: Inhibition of cyclooxygenase activity by diclofenac attenuates varicose remodeling of mouse veins
Figure 5. Influence of diclofenac-treatment on SMC activation in mouse auricle veins. Selected auricle tissue segments (4 d after vein ligation) containing remodeling veins were fixed, paraffin-embedded, cross-sectioned, and processed for immunostaining (nuclei were visualized by DAPI staining). While PCNA (proliferation marker, A, arrows), MMP-2 (B, arrows), and COX-2 (C, arrows) were detectable in cells of the remodeling veins, corresponding proteins were barely detected in diclofenac-treated auricles (arrows in D-F, scale bar: 50 µm).
